[projects] minor fixes, change supervisor for some projects
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@@ -11,27 +11,29 @@
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%%%%%%%%%%%%%% Questions %%%%%%%%%%%%%%%%%%%%%%%%%
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\section*{Reverse reconstruction of the stimulus that evoked a neuronal response.}
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To analyse the encoding properties of a neuron one often calculates the
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Spike-Triggered-Average (STA). The STA is the average stimulus that
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When analyzing neuronal responses we want to figure out which aspects of the stimulus are actually encoded in the neuronal response.
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One way to do this is to calculate the
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Spike-Triggered-Average (STA) and use it to reversely estimate which aspects of the stimulus are encoded in the resopnse.
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The STA is the average stimulus that
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led to a spike in the neuron:
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\[ STA(\tau) = \frac{1}{n} \displaystyle\sum_{i=1}^{n}{s(t_i - \tau)} \]
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where $n$ is the number of spikes and $t_i$ is the time of the
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$i_{th}$ spike. $\tau$ is a temporal shift relative to the spike
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time. For the beginning let $\tau$ assume values in the range
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$\pm50$\,ms. The STA can be estimated by cutting out snippets from the
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time.
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Another approach to understand the equation is to cut out snippets from the
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stimulus that are centered on the respective spike time and by
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subsequently averaging these stimulus snippets. The STA can be used to
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reconstruct the stimulus from the neuronal response (reverse
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reconstruction). The reconstructed stimulus can then be compared to
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the original stimulus and provides a good impression about the
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features that are encoded in the neuronal response.
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subsequently averaging these stimulus snippets.
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\begin{questions}
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\question In the accompanying data files you find the spike
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responses of a p-type electroreceptor afferent (P-unit) and a
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pyramidal neuron recorded in the hindbrain of the weakly electric
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fish \textit{Apteronotus leptorhynchus}. The respective stimuli are
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stored in separate files. The neron is stimulated with an amplitude
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stored in separate files. The neuron is stimulated with an amplitude
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modulation of the fish's own electric field. The stored stimulus
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trace is the modulator that is applied to the field and is
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dimensionless, i.e. it has no unit. The data is sampled with
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@@ -39,7 +41,15 @@ features that are encoded in the neuronal response.
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seconds. Start with the P-unit and, in the end, apply the same
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analyzes/functions to the pyramidal cell.
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\begin{parts}
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\part Estimate the STA and plot it. What does it tell?
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\part Familiarize yourself with the cellular responses and the stimulus.
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\part Estimate the STA and plot it. For the beginning let $\tau$ assume values in the range
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$\pm50$\,ms. What does it tell?
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\end{parts}
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\question The STA can be used to reconstruct the stimulus from the neuronal response (reverse
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reconstruction) by convolution of the spiking response with the STA. The reconstructed stimulus can then be compared to
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the original stimulus and provides a good impression about the
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features that are encoded in the neuronal response.
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\begin{parts}
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\part Implement a function that does the reverse reconstruction and uses the STA to reconstruct the stimulus.
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\part Implement a function that estimates the reconstruction quality.
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\part Test the robustness of the reconstruction: Estimate
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