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scientificComputing/projects/project_isicorrelations/isicorrelations.tex
2014-11-02 13:35:52 +01:00

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\documentclass[addpoints,10pt]{exam}
\usepackage{url}
\usepackage{color}
\usepackage{hyperref}
\pagestyle{headandfoot}
\runningheadrule
\firstpageheadrule
\firstpageheader{Scientific Computing}{Project Assignment}{11/05/2014
-- 11/06/2014}
%\runningheader{Homework 01}{Page \thepage\ of \numpages}{23. October 2014}
\firstpagefooter{}{}{}
\runningfooter{}{}{}
\pointsinmargin
\bracketedpoints
%\printanswers
%\shadedsolutions
%%%%% listings %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
\usepackage{listings}
\lstset{
basicstyle=\ttfamily,
numbers=left,
showstringspaces=false,
language=Matlab,
breaklines=true,
breakautoindent=true,
columns=flexible,
frame=single,
% captionpos=t,
xleftmargin=2em,
xrightmargin=1em,
% aboveskip=10pt,
%title=\lstname,
% title={\protect\filename@parse{\lstname}\protect\filename@base.\protect\filename@ext}
}
\begin{document}
%%%%%%%%%%%%%%%%%%%%% Submission instructions %%%%%%%%%%%%%%%%%%%%%%%%%
\sffamily
% \begin{flushright}
% \gradetable[h][questions]
% \end{flushright}
\begin{center}
\input{../disclaimer.tex}
\end{center}
%%%%%%%%%%%%%% Questions %%%%%%%%%%%%%%%%%%%%%%%%%
\begin{questions}
\question You are recording the activity of a neuron in response to
constant stimuli of intensity $I$ (think of that, for example,
of sound waves with intensities $I$). The neuron has an adaptatation
current that adapts the firing rate with a slow time constant down.
Explore the dependence of interspike interval correlations on the firing rate,
adaptation time constant and noise level.
\begin{parts}
\part The neuron is a neuron with an adaptation current.
It is implemented in the file \texttt{lifadaptspikes.m}. Call it
with the following parameters:
\begin{lstlisting}
trials = 10;
tmax = 50.0;
input = 10.0; % the input I
Dnoise = 1e-2; % noise strength
adapttau = 0.1; % adaptation time constant in seconds
adaptincr = 0.5; % adaptation strength
spikes = lifadaptspikes( trials, input, tmax, Dnoise, adapttau, adaptincr );
\end{lstlisting}
The returned \texttt{spikes} is a cell array with \texttt{trials} elements, each being a vector
of spike times (in seconds) computed for a duration of \texttt{tmax} seconds.
The input is set via the \texttt{input} variable, the noise strength via \texttt{Dnoise},
and the adaptation time constant via \texttt{adapttau}.
\part Measure the intensity-response curve of the neuron, that is the mean firing rate
as a function of the input for a range of inputs from 0 to 120.
\part Compute the correlations between each interspike interval $T_i$ and the next one $T_{i+1}$
(serial interspike interval correlation at lag 1). Plot this correlation as a function of the
firing rate by varying the input as in (a).
\part How does this dependence change for different values of the adaptation
time constant \texttt{adapttau}? Use values between 10\,ms and
1\,s for \texttt{adapttau}.
\part Determine the firing rate at which the minimum interspike interval correlation
occurs. How does the minimum correlation and this firing rate
depend on the adaptation time constant \texttt{adapttau}?
\part How do the results change if the level of the intrinsic noise \texttt{Dnoise} is modified?
Use values of 1e-4, 1e-3, 1e-2, 1e-1, and 1 for \texttt{Dnoise}.
\uplevel{If you still have time you can continue with the following question:}
\part How do the interspike interval distributions look like for the different noise levels
at some example values for the input and the adaptation time constant?
\end{parts}
\end{questions}
\end{document}