[projects] checked Jan B and Lukas projects

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2021-02-01 14:52:56 +01:00
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@@ -9,9 +9,6 @@
\input{../instructions.tex}
%%%%%%%%%%%%%% Questions %%%%%%%%%%%%%%%%%%%%%%%%%
\section{Estimation of activation curves of sodium channels}
Mutations in genes encoding ion channels can result in a variety of
neurological diseases like epilepsy, autism, or intellectual
disability. One way to find a possible treatment is to compare the
@@ -20,9 +17,10 @@ corresponding wild-type (non-mutated channel). Voltage-clamp
experiments are used to measure and describe the kinetics.
In the project you will compute and compare the activation curves of
the Nav1.6 wild-type (WT) channel and the A1622D mutation (the amino
acid Alanine (A) at the 1622nd position is replaced by Aspartic acid
(D)) that causes intellectual disability in humans.
sodium channel, in particular the Nav1.6 wild-type (WT) channel and
the A1622D mutation (the amino acid Alanine (A) at the 1622nd position
is replaced by Aspartic acid (D)) that causes intellectual disability
in humans.
\begin{questions}
\question In the accompanying datasets you find recordings of both