fixed many index entries
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@@ -26,15 +26,16 @@ parameters $\theta$. This could be the normal distribution
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defined by the mean $\mu$ and the standard deviation $\sigma$ as
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parameters $\theta$. If the $n$ independent observations of $x_1,
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x_2, \ldots x_n$ originate from the same probability density
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distribution (they are \enterm{i.i.d.} independent and identically
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distributed) then the conditional probability $p(x_1,x_2, \ldots
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distribution (they are \enterm[i.i.d.|see{independent and identically
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distributed}]{i.i.d.}, \enterm{independent and identically
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distributed}) then the conditional probability $p(x_1,x_2, \ldots
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x_n|\theta)$ of observing $x_1, x_2, \ldots x_n$ given a specific
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$\theta$ is given by
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\begin{equation}
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p(x_1,x_2, \ldots x_n|\theta) = p(x_1|\theta) \cdot p(x_2|\theta)
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\ldots p(x_n|\theta) = \prod_{i=1}^n p(x_i|\theta) \; .
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\end{equation}
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Vice versa, the \enterm{likelihood} of the parameters $\theta$
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Vice versa, the \entermde{Likelihood}{likelihood} of the parameters $\theta$
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given the observed data $x_1, x_2, \ldots x_n$ is
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\begin{equation}
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{\cal L}(\theta|x_1,x_2, \ldots x_n) = p(x_1,x_2, \ldots x_n|\theta) \; .
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@@ -57,7 +58,7 @@ The position of a function's maximum does not change when the values
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of the function are transformed by a strictly monotonously rising
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function such as the logarithm. For numerical and reasons that we will
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discuss below, we commonly search for the maximum of the logarithm of
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the likelihood (\enterm{log-likelihood}):
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the likelihood (\entermde[likelihood!log-]{Likelihood!Log-}{log-likelihood}):
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\begin{eqnarray}
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\theta_{mle} & = & \text{argmax}_{\theta}\; {\cal L}(\theta|x_1,x_2, \ldots x_n) \nonumber \\
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@@ -136,9 +137,10 @@ from the data.
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For non-Gaussian distributions (e.g. a Gamma-distribution), however,
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such simple analytical expressions for the parameters of the
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distribution do not exist, e.g. the shape parameter of a
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\enterm{Gamma-distribution}. How do we fit such a distribution to
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some data? That is, how should we compute the values of the parameters
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of the distribution, given the data?
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\entermde[distribution!Gamma-]{Verteilung!Gamma-}{Gamma-distribution}. How
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do we fit such a distribution to some data? That is, how should we
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compute the values of the parameters of the distribution, given the
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data?
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A first guess could be to fit the probability density function by
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minimization of the squared difference to a histogram of the measured
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@@ -289,10 +291,10 @@ out of \eqnref{mleslope} and we get
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To see what this expression is, we need to standardize the data. We
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make the data mean free and normalize them to their standard
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deviation, i.e. $x \mapsto (x - \bar x)/\sigma_x$. The resulting
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numbers are also called \enterm[z-values]{$z$-values} or $z$-scores and they
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have the property $\bar x = 0$ and $\sigma_x = 1$. $z$-scores are
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often used in Biology to make quantities that differ in their units
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comparable. For standardized data the variance
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numbers are also called \entermde[z-values]{z-Wert}{$z$-values} or
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$z$-scores and they have the property $\bar x = 0$ and $\sigma_x =
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1$. $z$-scores are often used in Biology to make quantities that
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differ in their units comparable. For standardized data the variance
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\[ \sigma_x^2 = \frac{1}{n} \sum_{i=1}^n (x_i - \bar x)^2 = \frac{1}{n} \sum_{i=1}^n x_i^2 = 1 \]
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is given by the mean squared data and equals one.
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The covariance between $x$ and $y$ also simplifies to
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