diff --git a/projects/project_face_selectivity/Makefile b/projects/project_face_selectivity/Makefile deleted file mode 100644 index a7b3726..0000000 --- a/projects/project_face_selectivity/Makefile +++ /dev/null @@ -1,3 +0,0 @@ -ZIPFILES= - -include ../project.mk diff --git a/projects/project_face_selectivity/auto/face_selectivity.el b/projects/project_face_selectivity/auto/face_selectivity.el deleted file mode 100644 index 0e5be37..0000000 --- a/projects/project_face_selectivity/auto/face_selectivity.el +++ /dev/null @@ -1,15 +0,0 @@ -(TeX-add-style-hook - "face_selectivity" - (lambda () - (TeX-add-to-alist 'LaTeX-provided-class-options - '(("exam" "a4paper" "12pt" "pdftex"))) - (TeX-run-style-hooks - "latex2e" - "../header" - "../instructions" - "exam" - "exam12") - (TeX-add-symbols - "ptitle")) - :latex) - diff --git a/projects/project_face_selectivity/face_selectivity.tex b/projects/project_face_selectivity/face_selectivity.tex deleted file mode 100644 index 029eae7..0000000 --- a/projects/project_face_selectivity/face_selectivity.tex +++ /dev/null @@ -1,127 +0,0 @@ -\documentclass[a4paper,12pt,pdftex]{exam} - -\newcommand{\ptitle}{Face-selectivity index} -\input{../header.tex} -\firstpagefooter{Supervisor: Marius G\"orner}{}% -{email: marius.goerner@uni-tuebingen.de} - -\begin{document} - -\input{../instructions.tex} - - -%%%%%%%%%%%%%% Questions %%%%%%%%%%%%%%%%%%%%%%%%% -\section{Estimating the face-selectivity index (FSI) of neurons} - - -In the temporal lobe of primates you can find neurons that respond -selectively to a certain type of object category. You may have heard -stories about the famous grandmother neurons which are supposed to -respond exclusively when the subject perceives a particular -person. Even though the existence of a grandmother neuron in the -strict sense is implausible, the concept exemplifies the observation -that sensory neurons within the ventral visual stream are tuned to -certain stimuli types. One of the most important and first visual -stimulus the newborn typically perceives is the mother's face. It is -believed that the early ubiquity of faces and their importance for -social interactions triggers the development of the so called -face-patch system within the temporal lobe of primates.\par -Your task here will be to estimate the \textit{selectivity index} -($SI$) of neurons that were recorded in the superior temporal sulcus -of a rhesus monkey during the visual presentation of objects of different -categories. - - -\begin{questions} -\question - In the accompanying datasets you find the - \texttt{spiketimes} of 184 neurons that were recorded during the visual - presentation of non-face like stimuli (tools, fruits, hands and - bodies) and averted and directed faces of humans and rhesus - monkeys. Each \texttt{.mat}-file contains the data of one neuron - which was recorded during multiple trials. Spike times are given in - ms relative to trial onset. The field \texttt{spiketimes} contains - cells that contain the the data of the trails. Each trial consists of - 400 ms of baseline recording (presentation of white noise) followed by 400 ms - of stimulus presentation. Each trial belongs to one object category, - trial identities can be found in the \texttt{*\_trials}-fields - (9 fields). - - \begin{parts} - \part - Illustrate the spiking activity of all neurons, sorted by object - category, in a raster plot. As a result you should get one plot - for each neuron subdevided in subplots for the different - categories. Mind that there are four categories that contain faces - (\texttt{averted\_human}, \texttt{face} (straight human face), - \texttt{monkey} (straight monkey face) and \texttt{gaze\_monkey}), - you may want to analyze them separately as well combined. Add also - a marker where the stimulus starts. - - \part - Estimate the time-resolved firing rate of each neuron for each - object category. Use at least two different methods - (e.g. instantaneous firing rate based on interspike intervals, - spike counting within bins (PSTH), kernel density estimation). Do - this individually for each trial and average afterwards in order - to obtain the standard deviation of the firing rates. Plot the - firing rates and their standard deviations on top of the raster - plots. Which of the methods appears to be a better representation - of the spike rasters? - - \part - Generate figures that show for each neuron the firing rates - belonging to each object category. Don't forget to add an - appropriate legend. - - \part - Next step is to examine the obtained firing rates for significant - modulations. - % First, normalize each response to baseline activity - % (first 400 ms). Why is the normalization useful? - % \par - Now, determine the periods within which the neurons activity - deviates from the baseline activity at least by $2*\sigma$. Do - this for each object category and mark the periods in the plots in - an appropriate way. Are there also inhibitory responses? \par - Describe qualitatively the response properties (phasic, tonic, are - there differences between neurons and/or stimulus categories?). - - \part - The $SI$ gives an estimate of how strong a neuron is tuned to the - chosen object categories. It is given by the neurons response - during the presentation of the one category compared to the other - category. - \begin{equation} - SI = \frac{ \mu_{\text{Response to category A}} - \mu_{ \text{Response - to category B}} } { \mu_{\text{Response to category A}} + \mu_{ \text{Response - to category B} } } - \end{equation} - $SI$ can take values between -1 and 1 which indicates tuning to - the one or to the other category. There are different - possibilities of how it can be estimated. The easiest way would be - to average the spike count during the whole time of stimulus - presentation. However, if responses are phasic you will - underestimate the $SI$. Therefor, you should limit the estimate to - periods of significant modulations. Use the periods determined in - (d). Store all obtained $SI$s within one variable. We are mainly - interested to identify face-selective neurons but feel free to test - the neurons for selectivity to other categories, as well. - - \part - Plot the distribution of $SI$ values and describe it - qualitatively. Does it indicate a continuum or a distinct - population of face-selective neurons. \par - Think about a statistical test that tells you whether a given - neuron is significantly modulated by one or the other category - (try different combinations of categories). List cells that show - significant modulation to faces and non-faces. Which is the - minimum SI that reaches significance when choosing - $\alpha = 0.05$? Is it an all or nothing selectivity? - - \end{parts} -\end{questions} - - - -\end{document}