From da1eb332a063dc9c7d3fb3c02aa6b94261786de6 Mon Sep 17 00:00:00 2001 From: maalaria Date: Sun, 13 Jan 2019 14:02:15 +0100 Subject: [PATCH] init project_face_selectivity --- projects/project_face_selectivity/Makefile | 3 + .../gaze_following.tex | 67 +++++++++++++++++++ 2 files changed, 70 insertions(+) create mode 100644 projects/project_face_selectivity/Makefile create mode 100644 projects/project_face_selectivity/gaze_following.tex diff --git a/projects/project_face_selectivity/Makefile b/projects/project_face_selectivity/Makefile new file mode 100644 index 0000000..a7b3726 --- /dev/null +++ b/projects/project_face_selectivity/Makefile @@ -0,0 +1,3 @@ +ZIPFILES= + +include ../project.mk diff --git a/projects/project_face_selectivity/gaze_following.tex b/projects/project_face_selectivity/gaze_following.tex new file mode 100644 index 0000000..24d4355 --- /dev/null +++ b/projects/project_face_selectivity/gaze_following.tex @@ -0,0 +1,67 @@ +\documentclass[a4paper,12pt,pdftex]{exam} + +\newcommand{\ptitle}{Adaptation time-constant} +\input{../header.tex} +\firstpagefooter{Supervisor: Jan Grewe}{phone: 29 74588}% +{email: jan.grewe@uni-tuebingen.de} + +\begin{document} + +\input{../instructions.tex} + + +%%%%%%%%%%%%%% Questions %%%%%%%%%%%%%%%%%%%%%%%%% +\section{Estimating the adaptation time-constant} +Stimulating a neuron with a constant stimulus for an extended period of time +often leads to a strong initial response that relaxes over time. This +process is called adaptation. Your task here is to +estimate the time-constant of the firing-rate adaptation in P-unit +electroreceptors of the weakly electric fish \textit{Apteronotus + leptorhynchus}. + +\begin{questions} + \question In the accompanying datasets you find the + \textit{spike\_times} of an P-unit electroreceptor to a stimulus of + a certain intensity, i.e. the \textit{contrast} which is also stored + in the file. The contrast of the stimulus is a measure relative to + the amplitude of fish's field, it has no unit. The data is sampled + with 20\,kHz sampling frequency and spike times are given in + milliseconds (not seconds!) relative to the stimulus onset. + \begin{parts} + \part Estimate for each stimulus intensity the PSTH. You will see + that there are three parts: (i) The first 200\,ms is the baseline + (no stimulus) activity. (ii) During the next 1000\,ms the stimulus + was switched on. (iii) After stimulus offset the neuronal activity + was recorded for further 825\,ms. Find an appropriate bin-width + for the PSTH. + + \part Estimate the adaptation time-constant for both the stimulus + on- and offset. To do this fit an exponential function + $f_{A,\tau,y_0}(t)$ to appropriate regions of the data: + \begin{equation} + f_{A,\tau,y_0}(t) = A \cdot e^{-\frac{t}{\tau}} + y_0, + \end{equation} + where $t$ is time, $A$ the (positive or negative) amplitude of the + exponential decay, $\tau$ the adaptation time-constant, and $y_0$ + an offset. + + Before you do the fitting, familiarize yourself with the three + parameter of the exponential function. What is the value of + $f_{A,\tau,y_0}(t)$ at $t=0$? What is the value for large times? How does + $f_{A,\tau,y_0}(t)$ change if you change either of the parameter? + + Which of the parameter could you directly estimate from the data + (without fitting)? + + How could you get good estimates for the other parameter? + + Do the fit and show the resulting exponential function together + with the data. + + \part Do the estimated time-constants depend on stimulus intensity? + + Use an appropriate statistical test to support your observation. + \end{parts} +\end{questions} + +\end{document}