diff --git a/Figures/firing_characterization-jb.py b/Figures/firing_characterization-jb.py index 8739f65..9a95b6c 100644 --- a/Figures/firing_characterization-jb.py +++ b/Figures/firing_characterization-jb.py @@ -348,9 +348,9 @@ lfsize = 8 ax3.text(x=-0.9, y=0.7, s='$\\uparrow$ AUC\n$\\downarrow$ rheobase', fontsize=lfsize) ax3.text(-0.95, 0.35, 'GOF', ha='right') ax3_TL = ax3.inset_axes([0.07, 0.6, 0.3, 0.2]) -plot_diff_sqrt(ax3_TL, b2=0.1, c2=200) +plot_diff_sqrt(ax3_TL, b2=0.09, c2=200) ax3_TL.set_ylim(inset_ylim) -ax3_TL.annotate('', (0.25, 15), (0.1, 27), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # +ax3_TL.annotate('', (0.25, 7), (0.085, 7), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # ax3_TL.annotate('', (0.55, 55), (0.3, 90), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # # top right ax3.text(x=0.22, y=0.7, s='$\\uparrow$ AUC\n$\\uparrow$ rheobase', fontsize=lfsize) @@ -358,16 +358,16 @@ ax3.text(0.95, 0.35, 'LOF/\nGOF?') ax3_TR = ax3.inset_axes([0.63, 0.6, 0.3, 0.2]) plot_diff_sqrt(ax3_TR, b2=0.4, c2=200) ax3_TR.set_ylim(inset_ylim) -ax3_TR.annotate('', (0.2, 15), (0.41, 15), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # +ax3_TR.annotate('', (0.17, 7), (0.41, 7), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # ax3_TR.annotate('', (0.8, 70), (0.6, 90), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # # bottom left ax3.text(x=-0.9, y=-0.95, s='$\\downarrow$ AUC\n$\downarrow$ rheobase', fontsize=lfsize) ax3.text(-0.95, -0.55, 'GOF/\nLOF?', ha='right') ax3_BL = ax3.inset_axes([0.07, 0.15, 0.3, 0.2]) -plot_diff_sqrt(ax3_BL, b2=0.07, c2=65) +plot_diff_sqrt(ax3_BL, b2=0.06, c2=65) ax3_BL.set_ylim(inset_ylim) -ax3_BL.annotate('', (0.25, 5), (0.07, 5), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # +ax3_BL.annotate('', (0.25, 7), (0.07, 7), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # ax3_BL.annotate('', (0.8, 80), (0.85, 55), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # # bottom right @@ -376,8 +376,8 @@ ax3.text(0.95, -0.55, 'LOF') ax3_BR = ax3.inset_axes([0.63, 0.15, 0.3, 0.2]) plot_diff_sqrt(ax3_BR, b2=0.4, c2=60) ax3_BR.set_ylim(inset_ylim) -ax3_BR.annotate('', (0.2, 15), (0.425, 10), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # -ax3_BR.annotate('', (0.65, 75), (0.8, 37.5), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # +ax3_BR.annotate('', (0.18, 7), (0.42, 7), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # +ax3_BR.annotate('', (0.7, 75), (0.8, 37.5), arrowprops=dict(arrowstyle="<|-", color=colorslist[2],lw=0.5, mutation_scale=5), zorder=-10) # diff --git a/Figures/firing_characterization_arrows.pdf b/Figures/firing_characterization_arrows.pdf index b32955b..d77050c 100644 Binary files a/Figures/firing_characterization_arrows.pdf and b/Figures/firing_characterization_arrows.pdf differ diff --git a/manuscript.tex b/manuscript.tex index b07bca2..85528db 100644 --- a/manuscript.tex +++ b/manuscript.tex @@ -290,10 +290,10 @@ Neuronal firing is heterogenous across the CNS and a set of neuronal models with \subsection*{Characterization of Neuronal Firing Properties} \begin{figure}[tp] \centering - \includegraphics[width=0.5\linewidth]{Figures/firing_characterization.pdf} +% \includegraphics[width=0.5\linewidth]{Figures/firing_characterization.pdf} \includegraphics[width=0.5\linewidth]{Figures/firing_characterization_arrows.pdf} \\\notenk{Re-work legend to be in line with new figure} - \\\notenk{Both done, which one do you like better? I think I like the legend one better, but I'm not sure what the best legend label for the red one I've labelled ``Altered'' is.}\notejb{I really like the arrows! Having two arrows is great. I Would make the lower one always horizontal to make it indicative for the rheobase. If space gets too narrow for this shift the fI curves further appart.} + \\\notenk{Both done, which one do you like better? I think I like the legend one better, but I'm not sure what the best legend label for the red one I've labelled ``Altered'' is.}\notejb{I really like the arrows! Having two arrows is great. I Would make the lower one always horizontal to make it indicative for the rheobase. If space gets too narrow for this shift the fI curves further appart.} \notenk{done!} \linespread{1.}\selectfont \caption[]{Characterization of firing with AUC and rheobase. (A) The area under the curve (AUC) of the repetitive firing frequency-current (fI) curve. (B) Changes in firing as characterized by \(\Delta\)AUC and \(\Delta\)rheobase occupy 4 quadrants separated by no changes in AUC and rheobase. Representative schematic fI curves in blue with respect to a reference fI curve (black) depict the general changes associated with each quadrant.}