diff --git a/gating_table.tex b/gating_table.tex index ce90b5f..ef64049 100644 --- a/gating_table.tex +++ b/gating_table.tex @@ -21,6 +21,7 @@ RS pyramidal, & \(\textrm{I}_{\textrm{Na}}\) inactivation \end{tabular}} - \caption[Gating Properties]{ For comparability to typical electrophysiological data fitting reported and for ease of further gating curve manipulations, a Boltzmann \(x_\infty = {\left(\frac{1-a}{1+{exp[{\frac{V-V_{1/2}}{k}}]}} +a\right)^j}\) with slope \(k\), voltage for half-maximal activation or inactivation (\(V_{1/2}\)), exponent \(j\), and persistent current \(0 \leq a \leq 1\) were fitted for the \cite{pospischil_minimal_2008} models where \(\alpha_x\) and \(\beta_x\) are used. Gating parameters for \(\textrm{I}_{\textrm{K}_{\textrm{V}}\textrm{1.1}}\ \) are taken from \cite{ranjan_kinetic_2019} and fit to mean wild type parameters in \cite{lauxmann_therapeutic_2021}. Model gating not listed are taken directly from source publication.} + \caption[Gating Properties]{ For comparability to typical electrophysiological data fitting reported and for ease of further gating curve manipulations, a sigmoid function (eqn.\ref{eqn:Boltz}) %Boltzmann \(x_\infty = {\left(\frac{1-a}{1+{exp[{\frac{V-V_{1/2}}{k}}]}} +a\right)^j}\) + with slope \(k\), voltage for half-maximal activation or inactivation (\(V_{1/2}\)), exponent \(j\), and persistent current \(0 \leq a \leq 1\) were fitted for the \citet{pospischil_minimal_2008} models where \(\alpha_x\) and \(\beta_x\) are used. Gating parameters for \(\textrm{I}_{\textrm{K}_{\textrm{V}}\textrm{1.1}}\ \) are taken from \citet{ranjan_kinetic_2019} and fit to mean wild type parameters in \citet{lauxmann_therapeutic_2021}. Model gating not listed are taken directly from source publication.} \label{tab:gating} \end{table} \ No newline at end of file